How do painkillers work?

You may take pain medicine for many reasons, whether it is a prescription or over-the-counter medicine. But have you ever wondered how these painkillers work in your body? Or have you ever wondered why there are different types of painkillers on the market?

There is a lot of information you need to know Pain management drugsThis is why we mentioned some important aspects of painkillers that you need to know. Read the article to learn about the types of painkillers, their role in your body, and what conditions require painkillers. So, let us discuss them.

What are painkillers?

These are medicines that can relieve pain. You can find many painkillers in the medical world. Not to mention, all these painkillers have different brand names.

You can take the following medicines:

• By injection

• Oral, such as tablets, capsules and liquids

• Through the back passage (rectum)

Some painkillers are available in the following forms ointment, cream, Or patch. Although there are a variety of medicines to choose from, you can find three main types that are effective for different types of pain and work in different ways.

Let’s discuss Types of Pain management drugs.

Non-steroidal anti-inflammatory drugs

Non-steroidal anti-inflammatory drugs or non-steroidal anti-inflammatory drugs are common and most commonly used analgesics for the treatment of pain associated with different health conditions such as arthritis. You may already be familiar with over-the-counter, over-the-counter NSAIDs, such as ibuprofen and aspirin.

These drugs not only relieve pain, but also reduce fever and inflammation. These drugs also help prevent blood clotting, which is necessary in some cases and harmful in others.

For example, when they reduce blood clotting, some non-steroidal anti-inflammatory drugs such as aspirin can benefit heart disease. Unfortunately, people with heart disease are more likely to bruise. These drugs also increase the risk of stomach upset, nausea, and ulcer problems. In addition, some people may also struggle due to its impact on kidney function.

Some common examples of NSAIDs include diclofenac and naproxen. Doctors usually prescribe low-dose non-steroidal anti-inflammatory drugs to limit their blood clotting properties, especially for those who have experienced a heart attack in the past.


It is also one of the most famous and common analgesics for pain and pain relief. These drugs are also the most effective in reducing high temperatures.

paracetamol It is usually used in combination with other analgesics and anti-disease drugs. This medicine is the best solution to various flu and cold health problems. Some doctors also recommend that you use this medication in small doses during breastfeeding and pregnancy.

You can find paracetamol under the brands Panadol, Medinol, Hedex and Disprol.


Sometimes opioids are called anesthetics. These are medicines prescribed by doctors to solve severe and persistent pain. Generally speaking, patients with chronic back pain and headaches need to take opioids. Opioids are also recommended for patients who experience chronic pain due to cancer or recovering from surgery. Healthcare providers also prescribe these drugs to children and adults who have been injured as a result of sports or who have experienced serious car accidents, falls, and other accidents.

There are two types of opioids, strong and weak. Some common weak opioids are dihydrocodeine and codeine. Examples of strong opioids include tramadol, pethidine, morphine, and oxycodone. If you take these two opioids without consulting a doctor, they will have adverse effects.

Different types of painkillers can be combined to make a pill, such as paracetamol plus codeine (co-codamol). In addition to the above drugs, some antiepileptic drugs and antidepressants also help treat neuropathic pain.

How do painkillers work?

All the mentioned types of painkillers work in different ways. They use different methods to treat your pain. It should be noted that not every medicine can treat every type of pain. This is why it is necessary to consult a doctor to prescribe the correct medicine for you.

Non-steroidal anti-inflammatory drugs

For non-steroidal anti-inflammatory drugs, they block or inhibit the action of enzymes or chemicals called cyclooxygenase (COX) enzymes. These chemicals help develop other enzymes called prostaglandins. This chemical is related to the development of inflammation and pain in the injured or injured area. In this way, the decrease in prostaglandin production reduces inflammation and pain. However, it must be noted that not every type of NSAID has a similar effect.


No one knows the exact process and effects of paracetamol in your body. However, paracetamol is believed to work by inhibiting COX enzymes in the central nervous system (spine) and the brain. You also need to know that this medicine is only good for lowering high temperature, treating pain and reducing inflammation.


Opioids bind to receptors called opioid receptors that are found in the intestines, central nervous system, and other parts of the body. This will reduce your response to pain and the way you feel it. In addition, it can improve your pain tolerance.

Under what circumstances need painkillers?

We have already discussed that medical service providers will prescribe painkillers in cases of surgery and injuries. You may know that painkillers, also called analgesics, are one of the most commonly used drugs in the United States. The doctor prescribes different painkillers according to the intensity and type of pain.In case of minor problems, such as headaches or Muscle sprain, Over-the-counter (OTC) pain relievers may be beneficial to you.

Prescription analgesics (such as opioid analgesics) can help treat moderate to severe pain, such as trauma, surgery, especially chronic diseases such as rheumatoid arthritis or cancer.Other pain conditions where you can use painkillers include Backache, Childbirth, urinary tract infections and fibromyalgia.

Managing the side effects of painkillers

Pain medicine has its side effect. But you don’t need to worry, because doctors have other treatments to overcome the effects of drugs on your body. The following are some of the side effects you may experience.


Constipation is a common side effect after taking opioids. However, if you improve your diet and start to consume fluids and dietary fiber and exercise moderately, it can help you significantly. Stool softeners or laxatives may also help constipation.


Vomiting and nausea may occur in the first two days after taking opioids. If you encounter this problem, it is best to consult a doctor as soon as possible. They may prescribe anti-nausea therapy to treat your problem.

Drowsiness, calmness, or confusion

Some pain medications can cause drowsiness, sedation, or drowsiness in the first two days after taking them. After taking painkillers, patients may also feel disoriented, confused, or absent-minded. If you encounter this problem, please tell your healthcare provider immediately. They may reduce your dose, add another medicine, or change your medicine.

Slow breathing

When patients take high doses of painkillers, they may have to face breathing problems. But when the body gets used to the medicine, this side effect will disappear. Because of this possible problem, the doctor will monitor the patient when he is admitted to the hospital. In addition, if the problem is not resolved and becomes very uncomfortable, the doctor may change your medication, especially for cancer patients.

Other pain treatments

Alternative pain treatment can help you treat local pain. Lidocaine patch is a local pain relief method and a prescription drug.

In addition, if you do not recover from conventional treatment, your healthcare provider may recommend that you see a pain management specialist. Healthcare providers who specialize in pain management can try other methods, such as certain types of physical therapy or different types of medications. Some doctors also recommend the use of TENS, a technique that prevents pain by placing patches in the body.

SCS or spinal cord stimulation consists of a small device similar to a pacemaker. Health professionals will place it near the epidural space near the spine area. The devices send tiny electrical pulses so that they can interrupt the pain signals reaching the brain.

Bottom line

So now you know how different painkillers work. Although some pain medications are safe to use without a prescription, it is best to consult a healthcare provider before taking any medications. This is because a health professional can diagnose your health and recommend the most suitable treatment for your situation. It is also important to note that if you take certain types of painkillers for a long time, they can cause undesirable side effects. For all these reasons, find the best health professionals in your town and visit them for better and faster treatment.

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