The prize recognizes Dr. Orr’s innovative research targeting senescent cells to treat Alzheimer’s disease
NEW YORK, Sept. 22, 2022 /PRNewswire/ — The Alzheimer’s Drug Discovery Foundation (ADDF) has named Miranda E. OrrPhD, Assistant Professor of Gerontology and Geriatric Medicine at the Wake Forest University School of Medicine, as the recipient of the 2022 Melvin R. Goodes Prize for Excellence in Alzheimer’s Drug Development. The annual award includes $150,000 and will support Dr. Orr’s pioneering work targeting senescent cells to translate the biology of aging into effective treatments for Alzheimer’s disease.
Dr. Orr’s research is focused on how aging affects brain cells and contributes to neurodegeneration. Her work targets “zombie” or senescent cells, which develop mechanisms to avoid the natural death cycle that should come to all cells and instead live on, accumulating in the brain, causing brain inflammation and releasing damaging toxins.
“Dr. Orr’s research is a critical part of this pivotal moment in Alzheimer’s research, as the focus shifts toward how the biology of aging underlies Alzheimer’s disease,” says Dr.