As part of ‘Operation Nasal Vaccine’ to counter COVID-19 spread, ACM-001 booster vaccine administered to first subject in phase 1 safety and immunogenicity trial – QNT Press Release


SINGAPORE and BASEL, Switzerland and SYDNEY, July 29, 2022 /PRNewswire/ — ACM Biolabsa biotechnology company with operations in Singapore, Switzerland and Australiafocusing on the development of next generation vaccines for infectious diseases, personalized immunotherapy for cancer patients using its proprietary delivery platform (non-lipid, non-viral), today announced that the first subject has been dosed in the first–in–human Phase 1 trial of its clinical candidate vaccine, ACM-001, a 2nd generation adjuvanted SARS-CoV-2 spike protein (beta variant) vaccine with broad protection against variants of concerns, including delta and omicron demonstrated in a variety of preclinical studies (Clinicaltrials.gov identifier NCT05385991).

About the study: The vaccine is evaluated as a booster in a phase 1, dose escalation study comparing intramuscular versus intranasal administration of various doses of antigen and adjuvant in healthy adult volunteers who have previously received 3 doses of approved Covid vaccines.

“The start of this First-in-human trial is an important milestone for ACM Biolabs. Our next generation COVID-19 vaccine ACM-001, a nasal vaccine, can make a significant contribution to block infections and transmission. The current situation of high infection and reinfection rates despite repeated booster vaccinations reinforces the emerging consensus of the scientific community that there is a high need for an intranasal COVID vaccine,” said Dr. Madhavan NallaniChief Executive Officer of ACM Biolabs. “We are now very much looking forward to see our promising preclinical results translate in …

Full story available on Benzinga.com



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