[ad_1]
Taipei, November 27, 2021 /PRNewswire/ – After the inspiring opening speech “Future Prospects of Cancer Immunotherapy” by the Nobel Prize and Tang Laureate Professor. Honjo Taku At 14day Asia Pacific Federation of Pharmacological Societies (APFP) November 26, 2020 Tang Prize winners biopharmaceutical science lecture, co-organized by the Tang Prize Foundation and the American Pharmacological Society Taiwan, Occurred on 14day APFP 1:30 PM (GMT+8) November 27. PhD co-chair Wen-Chang Chang, Chairman of the Board of Directors of Taipei Medical University, Ph.D. Yun YeonThe Chair Professor of Taipei Medical University, this special lecture was given by three doctors who are winners of the 2020 Tang Ren Biopharmaceutical Science Award. Charles Dinarello, Mark Feldman, with Kishimoto Tadamitsu, Providing valuable information about the role of cytokines in inflammation and COVID-19 disease and possible treatments.
Dr. Dinarello’s first lecture was entitled “Interleukin-1: The Main Mediator of Systemic and Local Inflammation”, which began in 1971 when he purified leukocyte pyrogens from human leukocytes. Then it took him six years to identify two fevers-producing molecules, which were later named IL-1α and IL-1β. In 1977, the research results were published in the Proceedings of the National Academy of Sciences. For Dr. Dinarello, “this is an important step in the history of cytokine biology” because many people in the life sciences are encouraged to study the effects of the immune system on human physiology. Influence. As a result, cytokine biology has expanded rapidly. He also talked about “the history of cytokines being used as treatments has changed dramatically” after the early experiments in humans, and the focus shifted to “inhibition of cytokines, such as IL-1, such as TNF, such as IL-6” in order to help the audience understand With the complex network of IL-1 family pro-inflammatory molecules, Dr. Dinarello elaborated on the signal transduction of IL-1 family members, their pro-inflammatory and anti-inflammatory properties, and the symptoms of IL-1 family members. Different inflammatory diseases, so that the audience can correctly grasp the second half of the lecture “Clinical application of Il-1 blockers”. As Dr. Dinarello said, overproduction of IL-1 is a common cause of many diseases. On the other hand, IL-1Ra can inhibit IL-1α and β, and block…
The full story can be found on Benzinga.com
[ad_2]
Source link
